List of results achieved thanks to the Bioimis Program and method

Thanks to their studies and research the Bioimis Research Center has created a Nutritional Program that makes you lose weight effectively as well as ensuring complete safety in terms of health.

The Bioimis Scientific Staff has been devoting a great deal of energy and resources to ensure maximum outcome with an ever-growing innovative service.

The effects obtained from studies conducted in collaboration with researchers and Italian universities show that the Bioimis Nutritional Program proves to be a valid solution to rapidly and safely reduce excess weight by eating to fullness, without the need of weighing food or counting calories.

Below you will find a summary of the main results acquired by people who followed the Bioimis Nutritional Program. The links provide access to the complete documents for those interested in learning more.

Program effectiveness in terms of weight loss and complete blood tests1

Edited by the Bioimis Research Center in collaboration with Dr. Marchetti, D., freelancer in Statistics Research

The first study was carried out on a group of 1,836 people to consider the response in terms of both weight and health, after following a 60-day Bioimis Nutritional Program eating recommended food to satiety based on the biochemical properties and data communicated daily by each individual.
After a 60-day Program the following results were shown:
  • Weight

    about 13 kg less in men with a maximum loss of 40 Kg and on average 10 kg less in women with a maximum loss of 24 Kg;

  • BMI

    about 4.3 points less for males with a maximum loss of 11 points and on average 3.8 points less for females with a maximum loss of 9 points;

  • Total Cholesterol

    on average 5% decrease of the values compared to their initial value;

  • HbA1C (Glycated Hemoglobin) and Blood Glucose

    about 0.4 % decrease for the glycated hemoglobin and 10%  average decrease for the blood glucose;

  • Triglycerides

    28% average decrease compared with the initial values;

  • BUN (Blood Urea Nitrogen) Test and creatinine

    no alteration of the values that are averagely unchanged from their baseline.

Research composition on people who followed the Bioimis Nutritional Program

1836
People who followed the program

Research results in weight loss after a 60-day Program

13kg
Average weight loss
Men
10kg
Average weight loss
Women
40kg
Maximum weight loss
Men
24kg
Maximum weight loss
Women

Research results in BMI loss after a 60-day Program

4.3
Average point loss
Men
3.8
Average point loss
Women
11
Maximum point loss
Men
9
Maximum point loss
Women

Research results compared to people's initial values after a 60-day Program

5%
Total Cholesterol
Average loss
28%
Triglycerides
Average loss
4%
Glycated Hemoglobin
Average loss
10%
Blood Glucose
Average loss
0%
BUN
Average loss
0%
Creatinine
Average loss

See complete study

Program effectiveness against hypertension2

Edited by the Bioimis Research Center

High blood pressure is one of the most common diseases in industrialised countries and it affects about 20% of the adult population. It is characterised by the steady presence of arterial blood pressure values above the norm, considering 140 mmHg as the systolic blood pressure target (also known as top number) and 90 mmHg as the diastolic blood pressure target (also known as bottom number).

High blood pressure can occur in two different forms: primary/essential hypertension, in which it is not possible to identify a cause, and secondary hypertension that tends to appear suddenly.

It is known that essential arterial hypertension is often part of a more complex picture of diseases and risk factors called metabolic syndrome, of which it constitutes a diagnostic criterion.

Considering what is reported in literature with respect to blood pressure improvements in individuals subject to a proper diet, we conducted an analysis of the data provided by our customers during the Bioimis Nutritional Program in order to highlight consistency with these observations.

The monitoring was conducted on all the clients who started the Bioimis Nutritional Program in 2015 while taking medication for hypertension.

We therefore examined 528 hypertensive patients, 162 of which were males (30.7%) and 366 of which were females (69.3%) and took into account how often they communicated any therapy modification and, if this did take place, whether it implied a dosage increase or reduction.

In this regard, it appears that from the initial sample, 114 clients claimed they had reduced their blood pressure medication in accordance with their physician (21.7%), (33.3% of which were males and 66.7% of which were females); among these, 43.5% reported they reduced the dosage within 30 days from the beginning of the program, 36.5% between the second and third month and 19% after the 90-day Program.

In addition, 115 clients (21.8%) said that they have completely eliminated the medication, (27.8% of which were males and 72.2% of which were females); among these 19% of our customers got rid of it within 30 days from the beginning of the Program, 53% between the second and third month and 28% after the 90-day Program.

Research prospect on hypertensive subjects

528
Hypertensive individuals
162
Men
30.7%
366
Women
69.3%

Reduction or removal of high blood pressure medications

229
Positive results
43.5%
114
Reduced medication
21.7%
115
Removed medication
21.8%

Individuals who reduced their hypertension medication

114
People with reduced medication
34
20.1%
men
80
21.8%
women

Time frame before starting to reduce medication

30
Days
43.5%
60
Days
36.5%
90
Days
19%

Individuals who removed their hypertension medication

114
People with removed medication
32
19.7%
men
83
22.6%
women

Time frame before removing medication

30
Days
19%
60
Days
53%
90
Days
28%

See complete study

Program Effectiveness in terms of fatty liver indicators3

Edited by the Bioimis Research Center

Hepatic Steatosis, alias Fatty Liver, is a liver disease with different etiologies and it can be divided into alcoholic and non-alcoholic. In this second case, the root cause is given by excessive fat deposit (triglycerides) in the liver.

Evidence in literature has shown that the relationship between transaminases may lead to its alcoholic or non-alcoholic pathogenesis.

Furthermore, a hypothesis that is often indicated by nutrition experts against diets causing quick weight loss is that if weight loss is superior to 5 kg a month, they cause a confluence of fatty acids higher than the management capability of the organ. Excess acid fats will therefore be deposited in the liver, and lacking the means of being disposed, they will induce the appearance, or worsening, of steatosis.

For this purpose, we examined 1,067 customers, considering the values of AST and ALT in time on Day 0 and Day 60.

Even though no initial radiological diagnosis of steatosis was available and being unable to assess via ultrasound the situation of the liver in the two observation points, it can be concluded that the transaminases (i.e. the indicators of liver damage) averagely improved over time.

Moreover, the number of clients with potential NAFLD transaminases was reduced after 60 days' Program compared to the beginning, and this also works for those losing more than 10 kg in the first two months of the program.

See complete study

Safety in the consumption of proteins4

Edited by the Bioimis Research Center in collaboration with Dr. Bosco, G., Department of Biomedical Sciences - Laboratory of Human Physiology - University of Padua

Given that Bioimis allows a customised journey according to the type of diet our customers choose (e.g. omnivorous, vegetarian, no meat, no fish), for those who are omnivorous (thus eating both meat and fish) a study was carried out to demonstrate the safety in the consumption of animal protein.

Bioimis allows you to eat healthy and natural food to fullness, but above all calls out to follow a varied and balanced diet composed of carbohydrates, protein, fat and all the essential nutrients, according to the type of nutrition being followed by the individual.

So by virtue of the fact that in Bioimis there are no minimum quantities to be respected, if you eat very large doses of protein, your diet may become high-protein, but if you stick to normal portions it will result in a regular protein diet.

Carried out in collaboration with Dr. Gerardo Bosco, Department of Biomedical Sciences - Laboratory of Human Physiology - University of Padua, Italy, this research is designed to demonstrate that a possible intake of protein, higher than the dose required to achieve a state of satiety, will not damage your kidney.

Any recommended intake levels are reported in scientific literature only out of cautiousness. On the contrary, what gets reaffirmed several times in scientific papers are the negative effects that obesity and overweight cause to the whole organism.

See complete study

Improvement of lean mass at the expense of fat mass and performance enhancement5

Graduation thesis by Dr. Federico De Gennaro, the University of Turin, School of Medicine - Polo San Luigi Gonzaga

Another important fact that emerged in these various studies is that weight loss evaluated by Body Composition measurements was not characterised by lean mass loss but rather a noteworthy percentage improvement took place at the expense of fat mass, which was significantly reduced.

More in detail, the study was carried out at A.O.U. Nephrology Department San Luigi Gonzaga in Orbassano (Turin, Italy), where they run an outpatient center exclusively for patients with chronic kidney disease (CKD) and a small dialysis unit.

The study involved both individuals with CKD and healthy people, who were then compared with people following other diets. For those individuals following Bioimis the results were very positive.

In addition to this, a comparison was made on the Handgrip measurements (evaluation of hand muscle contraction force): results showed no strength loss, but rather performance improvement. This is a further sign of the good preservation of muscle mass.

See complete study

Introduction to studies carried out on the effectiveness of the Bioimis Program in patients with kidney disease

Although many do not know about it, before approaching any diet, people must make sure that it is safe for their body and especially their kidneys.

Kidneys are very sensitive to the changes occurring in our bodies, even to the ones that are food related.  Therefore these organs have been closely studied in depth because if they function well, then the whole body works efficiently.

A number of studies listed below have been carried out in collaboration with the Nephrology Hospital Department in Orbassano (Turin) and the University of Turin to show that the Bioimis Program allows you to achieve good weight loss results even in people with kidney disease, while keeping their health conditions unaltered.

New slimming pattern in severely obese patients undergoing hemodialysis6

Made in collaboration with the Nephrology Hospital Departmentb in Orbassano (Turin) and the University of Turin.

The study was accepted by and presented to the National Congress of the Italian Society of Nephrology held in Florence.
The observation on obese or overweight patients suffering from kidney disease has demonstrated the effectiveness of the Bioimis Program in reducing body weight and in improving some blood test parameters of the people taking part in the study.

See complete study

Results in obese patients on hemodialysis7

Made in collaboration with the Nephrology Hospital Department in Orbassano (Turin) and the University of Turin.

The study verified the results achieved by combining dialysis with an intensive weight-loss program, such as Bioimis, in obese or overweight people undergoing dialysis.

From this study it was found that patients on hemodialysis, under constant check, can follow weight loss programs and achieve good results, with no side effects.

See complete study

Results in obese patients with chronic kidney disease, with reduced salt content8

Made in collaboration with the Nephrology Hospital Departmentb in Orbassano (Turin) and the University of Turin.

The study wanted to show that the reduction of sodium in the Bioimis Nutritional journey leads to a threshold effect in obese patients with chronic kidney disease and baseline proteinuria greater than 0.5 g / day.

This means that up to a certain value of urinary excretion of sodium, protein loss and sodium removal are independent, but below a certain threshold these two phenomena begin to influence each other.

See complete study

Results in Patients on dialysis9

Made in collaboration with the Nephrology Hospital in Orbassano (Turin) and the University of Turin.

In this study we tried to have patients undergoing daily dialysis follow the Bioimis Nutritional Program.

People lost weight rapidly and achieved improvements in terms of acidosis because their dietary habits changed in a healthier way after having eliminated all pre-packaged foods containing additives.

The reduction in the amount of salt during meals resulted in the lowering of blood pressure in hypertensive patients.

See complete study

Quick weight loss in chronically obese or overweight patients10

Made in collaboration with the Nephrology Hospital in Orbassano (Turin) and the University of Turin.

A report was presented to the first course of CME Diabesity Working Group ERA-EDTA, held in Tenerife; its purpose was to verify the results obtained from a group of patients with Chronic Kidney Disease who had chosen to follow the Bioimis Nutritional Program.

It proved significant reduction in weight and good proteinuria control without serious metabolic abnormalities, suggesting, therefore, that rapid weight loss is possible even in chronically obese or overweight patients.

See complete study

Results in obese or overweight patients suffering from glomerular proteinuria diseases11

Made in collaboration with the Nephrology Hospital in Orbassano (Turin)  and the University of Turin.

A second report was presented to the first course of CME Diabesity Working Group ERA-EDTA held in Tenerife. Its purpose was to discuss the results obtained in obese or overweight patients suffering from glomerular proteinuria diseases with the use of two diets in sequence: an intense and short-term weight loss program followed by a low-protein and long-term diet.

Although still ongoing, this study suggests that a sequential combination of intense weight loss and a low-protein diet may be successful in the weight loss of these subjects, while still maintaining lean body mass and controlling hyper-filtration and proteinuria.

See complete study

Weight loss in chronic kidney diseases12

Made in collaboration with the Nephrology Hospital Departmentb in Orbassano (Turin) and the University of Turin.

The study published in the Nutrients magazine shows the case of a patient suffering from chronic kidney disease at the fourth stage. After several attempts to lose weight, this patient found the solution thanks to the Bioimis program.

It should be noted that the patient could not undergo kidney transplantation because of his overweight. Despite that, he managed to enter the transplant list thanks to his optimised physical conditions achieved by participating in the Bioimis program.

See complete study

Improvement of some cardiovascular risk indicators and some haematochemical parameters with Program13

Edited by Bioimis Research Center

The study was carried out by Dr. Luigi Teta during his Masters course in Nutrition Research Methodology at the University of Padua.

The results obtained were important in terms of weight loss and reduction of some cardiovascular risk indicators (body mass index, waist circumference); the patients also presented significant improvements in the hematochemical parameters normally used to monitor the progression of type 2 diabetes mellitus. In just two months, in fact, on average, patients presented a significant reduction in their fasting plasma glucose from 154 to 108 mg/dl and glycated haemoglobin from 57 to 45 mmol/mol.

See complete study

Assessment of body composition before and during Program14

Edited by Bioimis Research Center

The study was carried out by Dr. Lucrezia Zilio during her Masters course in Nutrition Research Methodology at the University of Padua.

The total sample, but also in detail the male and female samples, had a good weight loss in the first two months as well as a reduction in the BMI.

The results show that the lost kilos mostly correspond to the fat body mass, which has undergone a good reduction, while the lean body mass has been maintained and has even slightly increased.

See complete study
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